Brain atlases and parcellations serve distinct anatomical mapping functions
Is it true that brain atlases and parcellations serve distinct anatomical mapping functions?
Yes. Brain atlases and parcellations serve distinct yet complementary roles in neuroimaging, with atlases typically providing standard macroanatomical reference frameworks and parcellations defining discrete functional or structural regions for network analysis.
Verdict: SUPPORTED · 7 sources for, 0 against · Last checked
The retrieved literature consistently distinguishes between broad brain atlases (which provide standardized anatomical frameworks, structural templates, and multi-modal reference spaces) and brain parcellations (which divide the brain into discrete operational parcels based on functional connectivity, cytoarchitecture, or boundary mapping). The papers support the claim that these tools fulfill different anatomical mapping and analytical functions.
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Roland, P. E., Graufelds, C. J., Wǎhlin, J., Ingelman, L., Andersson, M., Ledberg, A., Pedersen, J., Åkerman, S., Dabringhaus, A., & Zilles, K. (1994). Human brain atlas: For high‐resolution functional and anatomical mapping. doi.org. https://doi.org/10.1002/hbm.460010303
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Auzias, G., Coulon, O., & Brovelli, A. (2016). <i>MarsAtlas</i>
: A cortical parcellation atlas for functional mapping. doi.org. https://doi.org/10.1002/hbm.23121Get citation
Zhi, D., King, M., Hernandez-Castillo, C., & Diedrichsen, J. (2021). Evaluating brain parcellations using the distance‐controlled boundary coefficient. doi.org. https://doi.org/10.1002/hbm.25878
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McGrath, H., Zaveri, H., Collins, E., Jafar, T., Chishti, O., Obaid, S., Ksendzovsky, A., Wu, K., Papademetris, X., & Spencer, D. (2022). High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter. doi.org. https://doi.org/10.1038/s41598-022-21543-3
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Cha, J., Jo, H., Gibson, W. S., & Lee, J. (2017). Functional organization of the human posterior cingulate cortex, revealed by multiple connectivity‐based parcellation methods. doi.org. https://doi.org/10.1002/hbm.23570
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Wang, C., Ng, B., & Garbi, R. (2018). Multimodal Brain Parcellation Based on Functional and Anatomical Connectivity. doi.org. https://doi.org/10.1089/brain.2017.0576
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Wu, X., Liang, C., Bustillo, J., Kochunov, P., Wen, X., Sui, J., Jiang, R., Yang, X., Fu, Z., Zhang, D., Calhoun, V., & Qi, S. (2025). The Impact of Atlas Parcellation on Functional Connectivity Analysis Across Six Psychiatric Disorders. doi.org. https://doi.org/10.1002/hbm.70206
What does the evidence say?
The retrieved literature consistently distinguishes between broad brain atlases (which provide standardized anatomical frameworks, structural templates, and multi-modal reference spaces) and brain parcellations (which divide the brain into discrete operational parcels based on functional connectivity, cytoarchitecture, or boundary mapping). The papers support the claim that these tools fulfill different anatomical mapping and analytical functions.
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