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the claim

Benzene exposure is harmful to human health

the verdict
SUPPORTED
the evidence backs this
Recorded sources
6 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that benzene exposure is harmful to human health?

Yes. Multiple scientific studies and reviews confirm that benzene exposure is harmful to human health, driving adverse outcomes such as hematotoxicity, metabolic disruption, epigenetic alterations, and increased cancer risks.

Verdict: SUPPORTED · 6 sources for, 0 against · Last checked

The analysis

The claim that benzene exposure is harmful to human health is extensively supported by multiple studies documenting its hematotoxicity, carcinogenicity, and mechanisms of cellular damage in humans and animal models. No papers refute the claim.

Evidence for · 6
Metabolome-wide association study of occupational exposure to benzene.
2021
The paper demonstrates that occupational benzene exposure alters metabolic pathways and increases oxidative stress.
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N, R., R, V., L, Z., W, H., S, Y., SM, R., MT, S., DP, J., M, R., Q, L., & DI, W. (2021). Metabolome-wide association study of occupational exposure to benzene.. doi.org. https://doi.org/10.1093/carcin/bgab089

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More for · 5
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review.
2022
The paper identifies benzene as a Group 1 human chemical carcinogen capable of inducing epigenetic alterations.
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S, G., G, C., KZ, G., IP, P., & I, R. (2022). Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review.. doi.org. https://doi.org/10.1016/j.mrrev.2021.108408

Sex Difference and Benzene Exposure: Does It Matter?
2022
The paper discusses the adverse health outcomes and hematological cancer risks associated with benzene exposure.
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D, P., P, M., S, P., D, C., B, P., & L, C. (2022). Sex Difference and Benzene Exposure: Does It Matter?. doi.org. https://doi.org/10.3390/ijerph19042339

Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review.
2023
The paper highlights that benzene exposure causes fetal abnormalities and hematological malignancies, targeting hematopoietic stem cell niches.
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NA, Y., Z, A. H., SB, B., & IS, T. (2023). Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review.. doi.org. https://doi.org/10.3390/ijms24076335

Chemopreventive Potential of Major Flavonoid Compound of Methanolic Bark Extract of <i>Saraca asoca</i> (Roxb.) in Benzene-induced Toxicity of Acute Myeloid Leukemia Mice.
2017
The paper uses a benzene-induced toxicity mouse model to study how benzene causes acute myeloid leukemia and cell cycle deregulation.
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MK, M., M, S., & D, N. (2017). Chemopreventive Potential of Major Flavonoid Compound of Methanolic Bark Extract of <i>Saraca asoca</i> (Roxb.) in Benzene-induced Toxicity of Acute Myeloid Leukemia Mice.. doi.org. https://doi.org/10.4103/pm.pm_326_15

iPSC-Derived Bronchial Airways-On-Chip for the Assessment of Cytokine Secretion Triggered by Volatile Organic Compounds.
2026
The paper demonstrates that prolonged benzene exposure triggers inflammatory cytokine secretion and mutagenic/carcinogenic effects in bronchial airway tissues.
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A, G., R, I., Y, H., A, A., S, S., R, A., J, S., & A, A. (2026). iPSC-Derived Bronchial Airways-On-Chip for the Assessment of Cytokine Secretion Triggered by Volatile Organic Compounds.. doi.org. https://doi.org/10.1021/acsbiomaterials.6c00056

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What does the evidence say?

The claim that benzene exposure is harmful to human health is extensively supported by multiple studies documenting its hematotoxicity, carcinogenicity, and mechanisms of cellular damage in humans and animal models. No papers refute the claim.

Receipt History
first checked05 Aug 2026
judged → SUPPORTED · 8405 Aug 2026
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