Anaerobic glycolysis produces lactate rather than lactic acid
Is it true that anaerobic glycolysis produces lactate rather than lactic acid?
Anaerobic glycolysis produces lactate rather than lactic acid at physiological pH because the molecule immediately dissociates into its conjugate base and a proton, meaning no citation is needed for this biochemical truism.
Verdict: COMMON KNOWLEDGE · 0 sources for, 0 against · Last checked
The claim addresses a fundamental biochemical fact regarding the dissociation of organic acids at physiological pH inside cells. Under physiological conditions, glycolysis yields lactate (the anion) rather than lactic acid due to its low pKa. Because this is a basic textbook reality and direct observation of biochemical equilibrium, it falls under common knowledge, requiring no citation of specific papers.
What does the evidence say?
The claim addresses a fundamental biochemical fact regarding the dissociation of organic acids at physiological pH inside cells. Under physiological conditions, glycolysis yields lactate (the anion) rather than lactic acid due to its low pKa. Because this is a basic textbook reality and direct observation of biochemical equilibrium, it falls under common knowledge, requiring no citation of specific papers.
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