ADHD is structurally and functionally associated with the Anterior Cingulate Cortex
Is it true that ADHD is structurally and functionally associated with the Anterior Cingulate Cortex?
Yes. Extensive neuroimaging evidence confirms that attention-deficit/hyperactivity disorder (ADHD) is structurally and functionally associated with abnormalities in the anterior cingulate cortex.
Verdict: SUPPORTED · 5 sources for, 0 against · Last checked
The claim is specific, empirical, and directly evaluated by multiple retrieved studies. Papers [0], [1], [5], [7], and [11] all provide strong evidence showing structural and functional associations between ADHD and the anterior cingulate cortex (ACC). There are no retrieved papers refuting this association. Thus, the evidence strongly supports the claim, yielding a 'SUPPORTED' balance verdict.
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Makris, N., Biederman, J., Monuteaux, M., & Seidman, L. (2009). Towards Conceptualizing a Neural Systems-Based Anatomy of Attention-Deficit/Hyperactivity Disorder. doi.org. https://doi.org/10.1159/000207492
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Bush, G. (2009). Dorsal Anterior Midcingulate Cortex: Roles in Normal Cognition and Disruption in Attention-Deficit/ Hyperactivity Disorder. doi.org. https://doi.org/10.1093/oso/9780198566960.003.0012
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N, P., Y, L., K, Q., IZ, P., Q, C., Z, Z., Y, C., L, L., MK, S., RK, M., MP, D., Y, C., A, F., & Q, G. (2026). Mapping ADHD Heterogeneity and Biotypes by Topological Deviations in Morphometric Similarity Networks.. doi.org. https://doi.org/10.1001/jamapsychiatry.2026.0001
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T, S., H, H., & M, S. (2026). Anterior cingulate cortex alterations in children and adolescents with Attention Deficit and Hyperactivity Disorder: a systematic review of neuroimaging studies.. doi.org. https://doi.org/10.1080/08039488.2026.2708719
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M, Ç., E, Y., SV, Ü., & S, T. (2026). Attenuated rightward hemispheric asymmetry in ADHD: structural MRI evidence from a normalized asymmetry index and its association with cognitive performance.. doi.org. https://doi.org/10.3389/fnins.2026.1764242
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