Acute flaccid myelitis is caused by polioviruses.
Is it true that acute flaccid myelitis is caused by polioviruses?
No. Acute flaccid myelitis is primarily associated with non-polio enteroviruses such as enterovirus D68 (EV-D68), not polioviruses.
Verdict: REFUTED · 0 sources for, 4 against · Last checked
The claim states that acute flaccid myelitis (AFM) is caused by polioviruses. Contemporary literature consistently identifies non-polio enteroviruses, predominantly enterovirus D68 (EV-D68), as the primary viral driver of recent AFM outbreaks. None of the provided papers link AFM to poliovirus; instead, they explicitly attribute it to EV-D68 or other enteroviruses. Therefore, the claim is refuted by the current evidence.
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PW, K. (2025). EV-D68 neurological disease: tipping the scales toward immunopathogenesis.. doi.org. https://doi.org/10.1172/jci195839
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KM, Z., MW, M., MT, I., MM, J., JD, R., & MJ, E. (2026). Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity.. doi.org. https://doi.org/10.7554/elife.108672
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IM, N., M, O., P, S., T, I., M, M., M, S., & H, O. (2026). Enterovirus D68 Detected in Hospitalized Children With Severe Acute Respiratory Infections in Zambia.. doi.org. https://doi.org/10.1111/irv.70305
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N, L., G, B., E, S., B, C., E, R., K, B., J, S., M, K., B, T., M, K., L, C., J, M., I, S., AW, R., K, B., CK, L., DA, W., & P, R. (2025). A case of enterovirus D68-associated acute flaccid myelitis in an immunocompromised adult, Australia.. doi.org. https://doi.org/10.1128/asmcr.00074-25
What does the evidence say?
The claim states that acute flaccid myelitis (AFM) is caused by polioviruses. Contemporary literature consistently identifies non-polio enteroviruses, predominantly enterovirus D68 (EV-D68), as the primary viral driver of recent AFM outbreaks. None of the provided papers link AFM to poliovirus; instead, they explicitly attribute it to EV-D68 or other enteroviruses. Therefore, the claim is refuted by the current evidence.
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