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the claim

Antidepressant use increases the risk of developing Parkinson's disease.

the verdict
INSUFFICIENT LEANING
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that antidepressant use increases the risk of developing Parkinson's disease?

Unclear. One prospective study reports a roughly 1.85-fold higher rate of Parkinson's disease among people initiating antidepressants, strongest in the first two years, and one 2024 review states antidepressants increase PD risk. Both are partial: the prospective study's authors suggest early depressive symptoms may themselves be an early sign of PD, and the review asserts the link without presenting primary data.

Verdict: PARTIAL LEAN · 2 sources for, 0 against · Last checked

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Evidence for · 2
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Use of antidepressants and the risk of Parkinson's disease: a prospective study - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1136/jnnp.2008.152983

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More for · 1
2024
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Zhang, P., Wei, J., Zhaoshun, L., Xingxuan, L., & Li, L. (2024). Study on the Mechanism of Gut Microbiota in the Pathogenetic Interaction Between Depression and Parkinson 's Disease.. doi.org. https://doi.org/10.1016/j.brainresbull.2024.111001

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