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Antidepressant use increases the risk of developing Parkinson's disease.
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INSUFFICIENT LEANING
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2 sources for · 0 against
Is it true that antidepressant use increases the risk of developing Parkinson's disease?
Unclear. One prospective study reports a roughly 1.85-fold higher rate of Parkinson's disease among people initiating antidepressants, strongest in the first two years, and one 2024 review states antidepressants increase PD risk. Both are partial: the prospective study's authors suggest early depressive symptoms may themselves be an early sign of PD, and the review asserts the link without presenting primary data.
Verdict: PARTIAL LEAN · 2 sources for, 0 against · Last checked
Evidence for · 2
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Use of antidepressants and the risk of Parkinson's disease: a prospective study - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1136/jnnp.2008.152983
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Zhang, P., Wei, J., Zhaoshun, L., Xingxuan, L., & Li, L. (2024). Study on the Mechanism of Gut Microbiota in the Pathogenetic Interaction Between Depression and Parkinson 's Disease.. doi.org. https://doi.org/10.1016/j.brainresbull.2024.111001
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