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the claim

Melatonin supplements lower cortisol levels.

the verdict
CONTESTED PARTIAL
Recorded sources
3 sources for · 1 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that melatonin supplements lower cortisol levels?

Partly. One small randomized trial in hemodialysis patients found salivary cortisol significantly lower with melatonin, and a supplement bundle containing melatonin lowered cortisol in female athletes, while a 1995 study found melatonin raised daytime cortisol in postmenopausal women and did not change it in young women. The evidence is mixed, narrow in population, and does not settle the general claim.

Verdict: CONTESTED PARTIAL · 3 sources for, 1 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 3
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Effects of Melatonin on Salivary Levels of Cortisol and Sleep Quality of Hemodialysis Patients: A Randomized Clinical Trial - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.18502/ijps.v16i3.6256

Evidence against · 1
1995
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Cagnacci, A., Soldani, R., & Yen, S. S. (1995). Melatonin enhances cortisol levels in aged but not young women. doi.org. https://doi.org/10.1530/eje.0.1330691

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More for · 2
2025
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Effect of personalized nutritional supplements on physiological and biochemical monitoring and training adaptability in female field hockey players during winter training. (2025). doi.org. https://doi.org/10.1728/4552.45507

2023
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Melatonin and vitamin D, two sides of the same coin, better to land on its edge to improve multiple sclerosis. (2023). doi.org. https://doi.org/10.1073/pnas.2219334120

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