Estrogen hormone therapy increases breast cancer risk in transgender women compared with cisgender men.

the verdict

SUPPORTED

the evidence backs this

Recorded sources

1 source for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that estrogen hormone therapy increases breast cancer risk in transgender women compared with cisgender men?

Yes. One source reports a 2019 Dutch study finding a 46-fold increased risk of breast cancer in transgender women on exogenous hormone therapy compared with cisgender men. The remaining retrieved items concern menopausal hormone therapy in cisgender women or unrelated outcomes and do not address the claim.

Verdict: SUPPORTED · 1 source for, 0 against · Last checked 3 Oct 2026

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 1

Breast cancer in a transgender woman undergoing gender-affirming exogenous hormone therapy -

Get citation

Breast cancer in a transgender woman undergoing gender-affirming exogenous hormone therapy - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1016/j.radcr.2023.04.032

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