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the claim

NAD+ supplementation causes weight loss in humans who take it orally.

the verdict
CONTESTED PARTIAL
Recorded sources
1 source for · 1 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that NAD+ supplementation causes weight loss in humans who take it orally?

Partly. A meta-analysis of randomized trials of NAD+ precursors reports no significant effect on body weight (though BMI decreased), while a separate study reports that maternal nicotinamide riboside supplementation during lactation enhanced postpartum weight loss. The evidence covers only part of the claim and points in both directions.

Verdict: CONTESTED PARTIAL · 1 source for, 1 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 1
NR Supplementation During Lactation: Benefiting Mother and Child
2019
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NR Supplementation During Lactation: Benefiting Mother and Child. (2019). doi.org. https://doi.org/10.1016/j.tem.2019.02.004

Evidence against · 1
The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials -
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The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.3389/fnut.2023.1208734

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