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the claim
Some antibiotics kill bacteria by targeting the enzyme DNA gyrase.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against
Is it true that some antibiotics kill bacteria by targeting the enzyme DNA gyrase?
Yes. Multiple well-established classes of antibiotics, including fluoroquinolones, exert their antibacterial effects by targeting bacterial DNA gyrase.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
The analysis
The claim is specific, testable, and supported by multiple retrieved papers detailing how distinct classes of antibacterial agents successfully inhibit bacterial DNA gyrase to achieve bacterial killing.
Evidence for · 3
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CA, M., JM, D., & N, O. (2026). Novel Bacterial Topoisomerase Inhibitors: A New Front in an Old War.. doi.org. https://doi.org/10.1016/j.jmb.2026.169892
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More for · 2
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CR, S., M, R., SK, P., B, D., D, B., & S, P. (2026). All-atoms MD simulations study of newly designed ciprofloxacin derivatives as potential bacterial DHPS and DNA gyrase inhibitors.. doi.org. https://doi.org/10.3389/fbinf.2026.1876643
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N, M., NK, S., HC, C., L, D., & T, N. (2026). Uncomplicated Cure: The New Era of Gonorrhea Therapy With Oral Zoliflodacin.. doi.org. https://doi.org/10.1097/mjt.0000000000002172
What does the evidence say?
The claim is specific, testable, and supported by multiple retrieved papers detailing how distinct classes of antibacterial agents successfully inhibit bacterial DNA gyrase to achieve bacterial killing.
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