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the claim

Chronic acid reflux increases the risk of esophageal cancer.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
2 sources for · 1 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that chronic acid reflux increases the risk of esophageal cancer?

Yes. Two sources directly state that chronic GERD leads to Barrett's esophagus and increases the risk of esophageal adenocarcinoma, and another links chronic acid reflux to Barrett's esophagus. One source notes that reduced acid secretion lowers reflux sequelae, a partial counterpoint.

Verdict: SUPPORTED · 2 sources for, 1 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 2
Cox2 and β-Catenin/T-cell Factor Signaling Intestinalize Human Esophageal Keratinocytes When Cultured under Organotypic Conditions
2011
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Kong, J., Crissey, M. A. S., Stairs, D. B., Sepulveda, A. R., & Lynch, J. P. (2011). Cox2 and β-Catenin/T-cell Factor Signaling Intestinalize Human Esophageal Keratinocytes When Cultured under Organotypic Conditions. doi.org. https://doi.org/10.1593/neo.11788

Evidence against · 1
Helicobacter pylori and Gastroesophageal Reflux Disease. In Practical Manual of Gastroesophageal Reflux Disease.
2013
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Helicobacter pylori and Gastroesophageal Reflux Disease. In Practical Manual of Gastroesophageal Reflux Disease.. (2013). hdl.handle.net. https://hdl.handle.net/11388/72403

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More for · 1
Gastroesophageal reflux disease.
2003
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Gastroesophageal reflux disease.. (2003). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/12620183

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