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the claim

Genes and the environment probably both play a role in the development of allergies.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
7 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that genes and the environment probably both play a role in the development of allergies?

Yes. Genes and environmental factors both play critical roles in the development of allergies, interacting dynamically to influence disease risk.

Verdict: SUPPORTED · 7 sources for, 0 against · Last checked

The analysis

The claim is specific, empirical, and contestable, passing Step 0. The retrieved literature consistently supports the role of both genetic susceptibility and environmental exposures (as well as their interactions) in various allergic conditions such as asthma, allergic rhinitis, and food allergies. Therefore, the evidence strongly supports the claim.

Evidence for · 7
1999
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Weiss, S. T. (1999). Gene by environment interaction and asthma. doi.org. https://doi.org/10.1046/j.1365-2222.1999.00017.x

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More for · 6
2026
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KY, L., HR, K., Z, L., M, H., YT, H., X, X., & SK, H. (2026). Multi-Dimensional Perspective of the Gene and Environmental Interaction in Asthma.. doi.org. https://doi.org/10.1007/s12016-026-09162-6

2026
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S, H., Z, Z., H, Z., K, Q., T, S., W, X., J, M., Y, Z., & J, R. (2026). Early life factors and genetic interactions in allergic rhinitis: a genome-wide study.. doi.org. https://doi.org/10.1186/s12887-026-07052-6

2026
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ID, E., L, B., I, N., MC, V., & ET, J. (2026). Epidemiology and Natural History of Eosinophilic Gastrointestinal Disorders: Insights Gained and Remaining Gaps.. doi.org. https://doi.org/10.1016/j.jaip.2026.06.027

2026
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M, R. & T, S. (2026). Early-Life Nutrition: The Interplay of Nutritional, Microbial, Genetic, and Environmental Factors in Food Allergy Development and Prevention.. doi.org. https://doi.org/10.3390/nu18183026

2026
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KM, O., E, B., N, P., IF, S., JA, S., A, G., DM, A., JE, G., GK, K. H., CC, J., J, W., J, H., NW, L., 4th, S. C., & Jr, B. J. (2026). The Michigan Sibling Immunity Birth Study (M-SIBS): Study design protocol for a unique food allergy birth cohort.. doi.org. https://doi.org/10.1016/j.jacig.2026.100721

2026
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T, B., N, L., AL, P., PD, S., A, C., TL, B., C, D. B., L, K., C, P., S, T., S, T., & D, V. (2026). Oxidative stress as a pathway linking maternal phthalate and bisphenol exposure to childhood allergy and lung function: Mediation and interaction analyses.. doi.org. https://doi.org/10.1016/j.envres.2026.124607

What does the evidence say?

The claim is specific, empirical, and contestable, passing Step 0. The retrieved literature consistently supports the role of both genetic susceptibility and environmental exposures (as well as their interactions) in various allergic conditions such as asthma, allergic rhinitis, and food allergies. Therefore, the evidence strongly supports the claim.

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