Early menarche, late age at first birth, and late menopause are major risk factors for breast cancer.

the verdict

SUPPORTED

the evidence backs this

Recorded sources

3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that early menarche, late age at first birth, and late menopause are major risk factors for breast cancer?

Yes. Established epidemiological evidence confirms that early menarche, late age at first birth, and late menopause are significant risk factors for developing breast cancer.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked 3 Oct 2026

The analysis

The retrieved papers consistently support the well-established consensus that early menarche, late menopause, and reproductive milestones modulate breast cancer risk.

Evidence for · 3

Age at menarche, age at menopause, height and obesity as risk factors for breast cancer: Associations and interactions in an international case‐control study

1990

Wike et al. (1990) found that both early menarche and late age at menopause significantly increase breast cancer risk.

Get citation

Hsieh, C., Trichopoulos, D., Katsouyanni, K., & Yuasa, S. (1990). Age at menarche, age at menopause, height and obesity as risk factors for breast cancer: Associations and interactions in an international case‐control study. doi.org. https://doi.org/10.1002/ijc.2910460508

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More for · 2

Relationship between Age Maximum Height Is Attained, Age at Menarche, and Age at First Full-Term Birth and Breast Cancer Risk

2007

The 2007 prospective cohort analysis confirms that early menarche and related pubertal events are well-established risk factors for breast cancer.

Get citation

Li, C. I., Littman, A. J., & White, E. (2007). Relationship between Age Maximum Height Is Attained, Age at Menarche, and Age at First Full-Term Birth and Breast Cancer Risk. doi.org. https://doi.org/10.1158/1055-9965.epi-07-0242

1988

Early Japanese population survey data (1988) similarly identified underlying environmental and physical factors associated with late menopause and early menarche as breast cancer risk factors.

Get citation

Kato, I., Tominaga, S., & Suzuki, T. (1988). Factors Related to Late Menopause and Early Menarche as Risk Factors for Breast Cancer. doi.org. https://doi.org/10.1111/j.1349-7006.1988.tb01573.x

What does the evidence say?

The retrieved papers consistently support the well-established consensus that early menarche, late menopause, and reproductive milestones modulate breast cancer risk.

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