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the claim

Systemic biologics, systemic nonbiologics, and phototherapy for psoriasis are associated with known harms defined in clinical practice guidelines.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that systemic biologics, systemic nonbiologics, and phototherapy for psoriasis are associated with known harms defined in clinical practice guidelines?

Yes. Clinical practice guidelines and accompanying literature widely document that systemic biologics, nonbiologics, and phototherapy used for psoriasis carry well-defined risks of adverse events and harms.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The retrieved literature consistently supports the claim that systemic biologics, nonbiologics, and phototherapy for psoriasis are associated with well-characterized adverse effects documented in clinical practice guidelines (e.g., immunosuppressive risks, organ toxicity, and guideline toxicity management).

Evidence for · 3
Risk of herpes zoster associated with biological therapies for psoriasis and psoriatic arthritis: A systematic review and meta-analysis.
2021
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A, Z., Y, C., N, S., & Y, Y. (2021). Risk of herpes zoster associated with biological therapies for psoriasis and psoriatic arthritis: A systematic review and meta-analysis.. doi.org. https://doi.org/10.1097/md.0000000000027368

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More for · 2
Translating the 2020 AAD-NPF Guidelines of Care for the Management of Psoriasis With Systemic Nonbiologics to Clinical Practice
2021
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Chat, V. S., Uppal, S. K., Kearns, D. G., Han, G., & Wu, J. J. (2021). Translating the 2020 AAD-NPF Guidelines of Care for the Management of Psoriasis With Systemic Nonbiologics to Clinical Practice. doi.org. https://doi.org/10.12788/cutis.0177

Clinical practice guideline for psoriasis management in Latin America.
2026
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F, V., JR, C. A., D, K., AM, L., KDR, M. G., G, M., ES, R. Z., M, F., S, C., C, C., PJ, C., C, C., R, F., S, M., L, I. B., JC, C., & J, O. (2026). Clinical practice guideline for psoriasis management in Latin America.. doi.org. https://doi.org/10.1016/j.abd.2026.501449

What does the evidence say?

The retrieved literature consistently supports the claim that systemic biologics, nonbiologics, and phototherapy for psoriasis are associated with well-characterized adverse effects documented in clinical practice guidelines (e.g., immunosuppressive risks, organ toxicity, and guideline toxicity management).

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