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Rheumatoid arthritis is associated with lower bone mineral density and a higher risk of osteoporosis.
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INSUFFICIENT LEANING
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7 sources for · 0 against
Is it true that rheumatoid arthritis is associated with lower bone mineral density and a higher risk of osteoporosis?
Unclear. Several peer-reviewed items and reference works state or assume that rheumatoid arthritis is linked to lower bone mineral density and higher osteoporosis risk, including a cohort finding lower hip BMD with erosions and a clinic cohort reporting 65.8% low BMD among RA patients. However, these are single-cohort or background statements rather than a general quantitative demonstration of the association.
Verdict: PARTIAL LEAN · 7 sources for, 0 against · Last checked
Evidence for · 7
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Rheumatoid arthritis. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Rheumatoid_arthritis
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More for · 6
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A Clinical Evaluation of the Role of Autoimmunity in the Relation Between Erosions and Bone Mineral Density in Rheumatoid Arthritis. (2024). hal.univ-lorraine.fr. https://doi.org/10.3390/biomedicines12102376
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The Impact of Rheumatoid Arthritis on Bone Loss: Links to Osteoporosis and Osteopenia - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.7759/cureus.17519
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JM, B., M, P., T, W., K, S., V, G., & S, H. (2026). Impact of immunosuppressive therapy and clinical risk factors on the prevalence of low bone mineral density in rheumatic diseases.. doi.org. https://doi.org/10.3389/fmed.2026.1897856
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Allard-Chamard, H., Carrier, N., Dufort, P., Durand, M., Brum-Fernandes, A. d., & Boire, G. (2020). Osteoclasts and their circulating precursors in rheumatoid arthritis: Relationships with disease activity and bone erosions. doi.org. https://doi.org/10.1016/j.bonr.2020.100282
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Chen, Y., Chen, H., Huang, W., Liao, T., Chen, J., & Chao, W. (2017). Tocilizumab potentially prevents bone loss in patients with anticitrullinated protein antibody-positive rheumatoid arthritis. doi.org. https://doi.org/10.1371/journal.pone.0188454
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B, U., E, S., & N, Ş. (2026). Anticholinergic burden and bone health in rheumatoid arthritis.. doi.org. https://doi.org/10.1590/1806-9282.20260191
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