Adverse social determinants of health are associated with a higher risk of dementia in people with and without type 2 diabetes, according to two large national cohort studies.

Is it true that adverse social determinants of health are associated with a higher risk of dementia in people with and without type 2 diabetes, according to two large national cohort studies?

Unclear. Two large cohort studies (UK Biobank/NHANES and HRS/ELSA) report that adverse social determinants are associated with higher dementia risk, and one All of Us cohort reports the same in adults with type 2 diabetes. None of the retrieved items covers the claim's full scope of people both with and without type 2 diabetes.

Verdict: PARTIAL LEAN · 3 sources for, 0 against · Last checked 2 Oct 2026

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

MBBS, J. Z., PhD, Y. Z., MBBS, K. Z., MS, R. L., MS, X. Z., & PhD, P. Y. (2024). Associations of social determinants of health with life expectancy and future health risks among individuals with type 2 diabetes: two nationwide cohort studies in the UK and USA. doi.org. https://doi.org/10.1016/s2666-7568(24)00116-8

LU, Y., LI, D., & YOSHIDA, Y. (2026). 2263-P: Independent Association of Social Determinants of Health Score and Risk of Mild Cognitive Impairment and Dementia among People with Type 2 Diabetes: Findings from the All of Us Research Program. doi.org. https://doi.org/10.2337/db26-2263-p

Aravena, J. M., Chen, X., & Levy, B. R. (2025). Unequal expression: Social position modulates APOE genotype risk of dementia. doi.org. https://doi.org/10.1371/journal.pone.0335846