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Insulin resistance is associated with high cholesterol levels.
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CONTESTED PARTIAL
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5 sources for · 1 against
Is it true that insulin resistance is associated with high cholesterol levels?
Partly. Several studies link insulin resistance to dyslipidemia or to elevated LDL and remnant cholesterol, but others find insulin resistance acting independently of LDL cholesterol or associated with lower HDL cholesterol. The evidence covers parts of the claim rather than settling whether insulin resistance is associated with high cholesterol levels.
Verdict: CONTESTED PARTIAL · 5 sources for, 1 against · Last checked
Evidence for · 5
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Insulin resistance. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Insulin_resistance
Evidence against · 1
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Impact of insulin resistance on enhanced monocyte adhesion to endothelial cells and atherosclerogenesis independent of LDL cholesterol level. (2010). doi.org. https://doi.org/10.1016/j.bbrc.2010.04.031
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More for · 4
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Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. (2004). doi.org. https://doi.org/10.1194/jlr.m300368-jlr200
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Relation Among the Plasma Triglyceride/High-Density Lipoprotein Cholesterol Concentration Ratio, Insulin Resistance, and Associated Cardio-Metabolic Risk Factors in Men and Women. (2012). doi.org. https://doi.org/10.1016/j.amjcard.2012.02.016
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The Pro12Ala substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia. (2000). hal.science. https://doi.org/10.1016/S0021-9150(99)00433-5
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Insulin Resistance in Patients with Stroke is Related to Visceral Fat Obesity and Adipocytokines. (n.d.). cir.nii.ac.jp. https://doi.org/10.1016/j.jstrokecerebrovasdis.2008.01.004
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