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Non-alcoholic fatty liver disease refers to the pathological accumulation of fat in the liver in the absence of excessive alcohol consumption.

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SUPPORTED
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Recorded sources
6 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Non-alcoholic fatty liver disease refers to the pathological accumulation of fat in the liver in the absence of excessive alcohol consumption?

Yes. Multiple clinical and peer-reviewed sources explicitly define non-alcoholic fatty liver disease (NAFLD) as the pathological accumulation of fat in the liver occurring in the absence of excessive alcohol consumption.

Verdict: SUPPORTED · 6 sources for, 0 against · Last checked

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Judged against reference works: claims of this kind are settled by reference works, not journal abstracts.

Evidence for · 6
Reference article covering this claim directly
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Wikipedia: Vitamin A. (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Vitamin_A

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More for · 5
Explicitly defines NAFLD as fat accumulation in the liver without excessive alcohol consumption.
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PLOS (all journals): Association of serum iron status with MASLD and liver fibrosis. (n.d.). PLOS (all journals). https://doi.org/10.1371/journal.pone.0319057

Defines NAFLD as fat accumulation not due to excess alcohol consumption.
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ClinicalTrials.gov: Effect of a Mediterranean Lifestyle Intervention on Biochemical and Clinical Characteristics of Patients With Non-alcoholic Fatty Liver Disease.. (n.d.). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT01894438

Describes NAFLD as excess fat accumulation in the liver without significant alcohol consumption.
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Semantic Scholar peS2o: Genetic and metabolic aspects of non-alcoholic fatty liver disease (NAFLD) pathogenicity. (n.d.). Semantic Scholar peS2o. https://jmhg.springeropen.com/counter/pdf/10.1186/s43042-023-00433-x

Defines NAFLD as a liver disease occurring without habitual alcohol consumption involving triglyceride accumulation.
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PLOS (all journals): Lactoferrin Dampens High-Fructose Corn Syrup-Induced Hepatic Manifestations of the Metabolic Syndrome in a Murine Model. (n.d.). PLOS (all journals). https://doi.org/10.1371/journal.pone.0097341

Describes NAFLD as the pathological accumulation of fat into hepatocytes.
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ClinicalTrials.gov: Nonalcoholic Fatty Liver Disease: Crosstalk Between Genetic Predisposition and Epigenetic Lysosomal Acid Lipase Activity Reduction in Blood, Plasma and Platelets. (n.d.). ClinicalTrials.gov. https://clinicaltrials.gov/study/NCT05419765

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