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the claim
Praziquantel is a drug used in mass drug administration programs for the treatment of schistosomiasis and the prevention of morbidity.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
12 sources for · 0 against
Is it true that Praziquantel is a drug used in mass drug administration programs for the treatment of schistosomiasis and the prevention of morbidity?
Yes. Praziquantel is widely recognized and utilized as the primary drug in mass drug administration programs aimed at treating schistosomiasis and preventing associated morbidity.
Verdict: SUPPORTED · 12 sources for, 0 against · Last checked
The analysis
Every retrieved paper explicitly states or assumes that praziquantel is the standard medication used in mass drug administration (MDA) programs for treating schistosomiasis and controlling morbidity in endemic regions. The evidence universally supports the claim without any contradictory findings regarding its primary purpose.
Evidence for · 12
Refers to hundreds of millions of doses of praziquantel administered through mass drug administration campaigns in schistosomiasis-endemic settings.
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Danso-Appiah, A., Owiredu, D., & Akuffo, K. O. (2024). Praziquantel-related visual disorders among recipients in mass drug administration campaigns in schistosomiasis endemic settings: Systematic review and meta-analysis protocol. doi.org. https://doi.org/10.1371/journal.pone.0300384
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More for · 11
Investigates the coverage and predictors of the uptake of mass drug administration of praziquantel chemotherapy for schistosomiasis.
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Kiesolo, F. N., Sampa, M., Moonga, G., Michelo, C., & Jacobs, C. (2023). Coverage and predictors of the uptake of the mass drug administration of praziquantel chemotherapy for schistosomiasis in a selected urban setting in Zambia. doi.org. https://doi.org/10.3389/fepid.2023.1168282
Assesses schistosomiasis infection levels years after mass drug administration with praziquantel.
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Imalele, E. E., Braide, E. I., Emanghe, U. E., & Osondu-Anyanwu, C. (2025). The burden of schistosomiasis among school-aged children in Ogoja, Nigeria: current level of infection years after mass drug administration with Praziquantel. doi.org. https://doi.org/10.4314/ahs.v24i4.9
Discusses regular mass drug administration with praziquantel against urogenital schistosomiasis implemented over two decades.
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S, K., NJ, v. D., NC, N., T, P., MN, A., KR, S., M, D., S, J., SM, A., AM, E., BL, W., LE, C., & SM, A. (2026). 20+ years of mass drug administration against urogenital schistosomiasis on the Zanzibar islands: Is praziquantel still efficacious?. doi.org. https://doi.org/10.64898/2026.08.13.26360376
Notes that praziquantel is a key component of schistosomiasis control programs recommended by the WHO.
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HM, M., T, E., & I, A. (2026). Therapeutic Management of Schistosomiasis in Pregnancy: A Comprehensive Review of Praziquantel Safety and Clinical Outcomes.. doi.org. https://doi.org/10.3390/biomedicines14092018
Acknowledges that praziquantel is the recommended treatment utilized in mass drug administration programs.
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M, K., RD, M., T, R., & N, S. (2026). Barriers in managing maternal schistosomiasis: a qualitative study of healthcare providers in Tanzania.. doi.org. https://doi.org/10.1093/inthealth/ihag001
Evaluates the feasibility of preventative chemotherapy with praziquantel in young children.
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E, M., AS, A., EA, N., D, S., SD, B., EA, S., N, D., F, A., G, S., H, A., G, H., M, A., P, A., & G, G. (2026). Non-Participation Undermines Mass Drug Administration Effectiveness and Sustains Urogenital Schistosomiasis Transmission in an Endemic Community in Ghana. doi.org. https://doi.org/10.64898/2026.08.03.26359546
Explores implementation fidelity of school-based preventive chemotherapy using praziquantel for schistosomiasis control.
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V, M., DK, A., S, R., A, G., M, L., F, F., A, R., JC, H., L, S., A, B., T, R., P, R., O, T., AO, Z., T, R., HG, R., EF, R., A, G., I, K., CF, R., J, M., RA, R., & D, F. (2026). Feasibility of paediatric schistosomiasis prevention with praziquantel, Madagascar.. doi.org. https://doi.org/10.2471/blt.25.295521
Notes that mass drug administration using praziquantel is central to efforts to eliminate schistosomiasis.
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H, M., BJ, M., M, V., & FN, G. (2026). Contextual barriers and facilitators influencing implementation fidelity of school-based preventive chemotherapy for schistosomiasis: A qualitative study in two endemic districts in the Central Region, Ghana.. doi.org. https://doi.org/10.1371/journal.pone.0348920
Evaluates the costs and implementation of community-based mass drug administration for schistosomiasis control using praziquantel.
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P, O., FD, C., J, O., E, O., BH, O., M, M., WL, C., T, A., & EM, N. (2026). Pooled amplicon sequencing for characterizing mutations in the praziquantel molecular target TRPM <sub>PZQ</sub> in schistosome populations from Western Kenya. doi.org. https://doi.org/10.64898/2026.08.04.742841
Examines schistosomiasis control implications following mass praziquantel administration campaigns.
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JM, B., A, K., E, G., I, M., R, P., CE, C., CG, M., S, K., C, K., A, F., A, M., HD, M., & AT, M. (2026). Cost analysis of implementing community-based mass drug administration for schistosomiasis control among adult individuals using community drug distributors in Ukerewe district council, North-Western Tanzania.. doi.org. https://doi.org/10.1371/journal.pntd.0014470
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Okete, J. A., Etta, E. E., Ikika, P. E., Akpe, T. E., & Onoja, B. O. (2026). Occurrence of snail intermediate host of schistosomiasis: implications for schistosomiasis control based on mass drug administration of praziquantel in Benue State, Nigeria. doi.org. https://doi.org/10.64898/2026.01.22.701117
What does the evidence say?
Every retrieved paper explicitly states or assumes that praziquantel is the standard medication used in mass drug administration (MDA) programs for treating schistosomiasis and controlling morbidity in endemic regions. The evidence universally supports the claim without any contradictory findings regarding its primary purpose.
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