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the claim

A genetic analysis found evidence that the gut bacteria Eggerthella and Hungatella contribute causally to major depressive disorder in humans.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that a genetic analysis found evidence that the gut bacteria Eggerthella and Hungatella contribute causally to major depressive disorder in humans?

Yes. A 2026 human study using data-driven causal inference in a large multicenter MDD cohort reports evidence that Eggerthella and Hungatella are potential causal contributors to major depressive disorder. Other retrieved items only show associations between these genera and depressive symptoms or psychiatric disorders, not causality.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

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Evidence for · 3
From gut to brain: data-driven evidence suggests causal contribution of gut-microbiota to major depressive disorder in humans.
2026
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L, F., AH, R., NR, W., SE, T., L, F., M, W., C, B., S, M., K, F., T, B., J, G., EJ, L., M, B., EE, N., D, M., A, A. V., F, S., F, T., P, U., & L, T. (2026). From gut to brain: data-driven evidence suggests causal contribution of gut-microbiota to major depressive disorder in humans.. doi.org. https://doi.org/10.1080/19490976.2026.2718589

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More for · 2
Role of the gut microbiome in three major psychiatric disorders -
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Role of the gut microbiome in three major psychiatric disorders - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1017/S0033291722000897

Gut microbiome-wide association study of depressive symptoms
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Gut microbiome-wide association study of depressive symptoms. (n.d.). cir.nii.ac.jp. https://doi.org/10.1038/s41467-022-34502-3

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