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the claim

Monosodium glutamate causes headaches and discomfort known as Chinese restaurant syndrome.

the verdict
CONTESTED PARTIAL
Recorded sources
3 sources for · 4 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that monosodium glutamate causes headaches and discomfort known as Chinese restaurant syndrome?

Partly. Evidence is mixed and partial: an older 1969 paper and a clinical report link high-dose MSG to headaches and Chinese restaurant syndrome, while a 2016 systematic review, a safety evaluation, and skeptical sources report that blinded human studies have not confirmed the causal link.

Verdict: CONTESTED PARTIAL · 3 sources for, 4 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 3
Chinese Restaurant Syndrome -
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Chinese Restaurant Syndrome - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.4103/0972-5229.198327

Evidence against · 4
Glutamate flavoring
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Glutamate flavoring. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Glutamate_flavoring

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More for · 2
Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome
1969
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Schaumburg, H. H., Byck, R., Gerstl, R., & Mashman, J. H. (1969). Monosodium L-Glutamate: Its Pharmacology and Role in the Chinese Restaurant Syndrome. doi.org. https://doi.org/10.1126/science.163.3869.826

The excitotoxic effect of monosodium glutamate on Zebra Fish (Danio rerio)
2023
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Malathi, N. (2023). The excitotoxic effect of monosodium glutamate on Zebra Fish (Danio rerio). zenodo.org. https://doi.org/10.5281/zenodo.11195175

More against · 3
Is monosodium glutamate (MSG) bad for you?
2011
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Is monosodium glutamate (MSG) bad for you?. (2011). skeptics.stackexchange.com. https://skeptics.stackexchange.com/questions/4270/is-monosodium-glutamate-msg-bad-for-you

Does monosodium glutamate really cause headache? : a systematic review of human studies.
2016
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Y, O. & Y, N. (2016). Does monosodium glutamate really cause headache? : a systematic review of human studies.. doi.org. https://doi.org/10.1186/s10194-016-0639-4

The safety evaluation of monosodium glutamate.
2000
Get citation
R, W. & JR, L. (2000). The safety evaluation of monosodium glutamate.. doi.org. https://doi.org/10.1093/jn/130.4.1049s

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