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the claim

A 2026 study screened a virtual library of more than 12 million compounds to identify histidine kinase inhibitors.

the verdict
SUPPORTED
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1 source for · 0 against

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Is it true that a 2026 study screened a virtual library of more than 12 million compounds to identify histidine kinase inhibitors?

Yes. A 2026 peer-reviewed study reports using amino acid mapping-based virtual screening of approximately 12 million commercially available compounds to identify novel histidine kinase inhibitors, yielding 714 candidates.

Verdict: SUPPORTED · 1 source for, 0 against · Last checked

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Evidence for · 1
Amino acid mapping–guided scaffold selection and hit identification of histidine kinase inhibitors from a virtual library of over 12 million compounds
2026
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Ishikawa, T., Eguchi, Y., Okajima, T., Igarashi, M., Ohira, S., Tsumura, K., Sakurai, K., Ishizaki, Y., Hayashi, C., Akter, S., Nakayama, J., Kohayakawa, C., Tani, A., Sawa, N., Katsumoto, T., Matsumoto, F., Haruta, J., & Utsumi, R. (2026). Amino acid mapping–guided scaffold selection and hit identification of histidine kinase inhibitors from a virtual library of over 12 million compounds. doi.org. https://doi.org/10.1038/s41429-026-00953-9

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