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the claim

ELISA tests are sensitive enough to quantify antigens in the nanogram per milliliter range.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that ELISA tests are sensitive enough to quantify antigens in the nanogram per milliliter range?

Yes. Multiple studies demonstrate that ELISA assays routinely achieve the sensitivity required to quantify antigens and antibodies in the nanogram per milliliter range.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The retrieved papers include multiple specific implementations of ELISA (and related immunoassays) that explicitly report quantitative ranges and detection limits within the nanogram per milliliter range (e.g., 4.61-431.37 ng/mL, lower limit of quantification at 4.79 ng/mL, and a linear range of 1-25 ng/mL). There is no contradictory evidence in the retrieved set.

Evidence for · 3
Precision Assay for Detection and Quantification of Anti-Prostate Specific Antigen Antibodies Using Indirect ELISA
2026
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Kumar, N., Kole, L., & Singh, A. K. (2026). Precision Assay for Detection and Quantification of Anti-Prostate Specific Antigen Antibodies Using Indirect ELISA. doi.org. https://doi.org/10.2174/0118715265342094250423103513

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More for · 2
Development of a Double-Antibody Sandwich ELISA for the Detection of HPV16 E6 Protein.
2026
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P, D., M, Y., X, W., H, W., W, Y., Y, W., J, Z., & A, W. (2026). Development of a Double-Antibody Sandwich ELISA for the Detection of HPV16 E6 Protein.. doi.org. https://doi.org/10.3390/diagnostics16132002

Development and Validation of an Antigen-Capture ELISA for Quantitative Detection of Donkey-Origin Rotavirus: Application in Vaccine Manufacturing Process Monitoring.
2026
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Z, Z., X, G., K, G., W, G., C, D., Y, Y., W, D., X, C., Y, L., & X, W. (2026). Development and Validation of an Antigen-Capture ELISA for Quantitative Detection of Donkey-Origin Rotavirus: Application in Vaccine Manufacturing Process Monitoring.. doi.org. https://doi.org/10.3390/microorganisms14091874

What does the evidence say?

The retrieved papers include multiple specific implementations of ELISA (and related immunoassays) that explicitly report quantitative ranges and detection limits within the nanogram per milliliter range (e.g., 4.61-431.37 ng/mL, lower limit of quantification at 4.79 ng/mL, and a linear range of 1-25 ng/mL). There is no contradictory evidence in the retrieved set.

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