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the claim
Fish oil supplementation increases the risk of colon cancer.
the verdict
INSUFFICIENT LEANING
Recorded sources
0 sources for · 5 against
Is it true that fish oil supplementation increases the risk of colon cancer?
Unclear. Several retrieved items address fish oil and colon cancer, but they are small animal or short-term human studies suggesting possible protective or mechanistic effects rather than an increased risk; none directly measures colon cancer incidence from fish oil supplementation.
Verdict: PARTIAL LEAN · 0 sources for, 5 against · Last checked
Evidence against · 5
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Do fish oil or omega-3 fatty acids increase the risk of cancer?. (2013). skeptics.stackexchange.com. https://skeptics.stackexchange.com/questions/17400/do-fish-oil-or-omega-3-fatty-acids-increase-the-risk-of-cancer
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More against · 4
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Kansal, S., Negi, A. K., & Agnihotri, N. (2012). Abstract B2: Supplementation of dietary fish oil induces apoptosis through activation of PPARγ and involves inhibition of angiogenesis in colon cancer. doi.org. https://doi.org/10.1158/1078-0432.mechres-b2
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Anti, M., Marra, G., Armelao, F., Bartoli, G., Ficarelli, R., Percesepe, A., Vitis, I. d., Maria, G., Sofo, L., Rapaccini, G. L., Gentiloni, N., Piccioni, E., & Miggiano, G. (1992). Effect of omega-3 fatty acids on rectal mucosal cell proliferation in subjects at risk for colon cancer.. doi.org. https://doi.org/10.1016/0016-5085(92)90021-P
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Heller, A. R., Rössel, T., Gottschlich, B., Tiebel, O., Menschikowski, M., Litz, R. J., Zimmermann, T., & Koch, T. (2004). Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients.. doi.org. https://doi.org/10.1002/ijc.20291
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Neilson, A., Ren, J., Hong, Y. H., Sen, A., Smith, W., Brenner, D., & Djuric, Z. (2011). EFFECT OF FISH OIL ON LEVELS OF R- AND S-ENANTIOMERS OF 5-, 12- AND 15-HYDROXYEICOSATETRAENOIC ACIDS IN MOUSE COLONIC MUCOSA. doi.org. https://doi.org/10.1080/01635581.2012.630168
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