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A multimodal MRI study found altered brain tissue microstructure and neurochemical profiles in people with long COVID and in people recovered from COVID-19.

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SUPPORTED
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Recorded sources
5 sources for · 0 against

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Is it true that a multimodal MRI study found altered brain tissue microstructure and neurochemical profiles in people with long COVID and in people recovered from COVID-19?

Yes. A 2025 multimodal MRI study directly reports altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals compared with healthy controls. Several other multimodal MRI studies report related brain alterations in COVID-19 survivors, though in narrower populations or tied to specific symptoms.

Verdict: SUPPORTED · 5 sources for, 0 against · Last checked

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Evidence for · 5
Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study.
2025
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K, T., S, M., M, I., & L, B. (2025). Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study.. doi.org. https://doi.org/10.1016/j.bbih.2025.101142

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More for · 4
Multimodal MRI analysis of COVID-19 effects on pediatric brain
2025
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Multimodal MRI analysis of COVID-19 effects on pediatric brain. (2025). doi.org. https://doi.org/10.1038/s41598-025-96191-4

Brain correlates of perceived cognitive impairment after covid-19 infection: a multimodal MRI study.
2023
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Bettonagli, V., Paolini, M., Palladini, M., Mazza, M. G., Guerini, P. R., & Poletti, S. (2023). Brain correlates of perceived cognitive impairment after covid-19 infection: a multimodal MRI study.. doi.org. https://doi.org/10.1192/j.eurpsy.2023.319

The Sense of Smell atlas: from creation to the first application for investigating COVID-19-related anosmia with quantitative multimodal-MRI
2025
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The Sense of Smell atlas: from creation to the first application for investigating COVID-19-related anosmia with quantitative multimodal-MRI. (2025). doi.org. https://doi.org/10.58530/2025/0398

Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol
2025
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Zhang, M., Niu, X., Liu, T., Zheng, C., Yuan, H., & Zhu, Y. (2025). Multicentre, multitime, multidimension, prospective follow-up cohort study on patients during the first wave of COVID-19 in China: a study protocol. doi.org. https://doi.org/10.1136/bmjopen-2023-083023

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