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the claim

Sucralose causes epigenetic changes in mice that are passed on to later generations.

the verdict
INSUFFICIENT LEANING
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Sucralose causes epigenetic changes in mice that are passed on to later generations?

Unclear. Two sources report that sucralose exposure in mice produced changes in gut microbiota, short-chain fatty acids and gene expression that were detectable in the F1 and F2 generations, but neither demonstrates actual epigenetic marks being inherited.

Verdict: PARTIAL LEAN · 2 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 2
Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations -
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Artificial and natural non-nutritive sweeteners drive divergent gut and genetic responses across generations - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.3389/fnut.2026.1694149

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More for · 1
Negative effects of artificial sweeteners may pass on to next generation, mouse research suggests
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Negative effects of artificial sweeteners may pass on to next generation, mouse research suggests. (n.d.). frontiersin.org. https://www.frontiersin.org/news/2026/04/10/negative-effects-artificial-sweeteners-may-pass-next-generation-frontiers-nutrition

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