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the claim
SSRI antidepressants increase blood pressure in patients who take them.
the verdict
REFUTED
the evidence says no
Recorded sources
0 sources for · 3 against
Is it true that SSRI antidepressants increase blood pressure in patients who take them?
No. A peer-reviewed review reports that patients prescribed SSRIs showed no significant blood pressure changes compared with placebo, and a separate meta-analysis notes escitalopram slightly decreased blood pressure and calls the SSRI-blood pressure relationship ambiguous. An animal study likewise found chronic escitalopram did not affect blood pressure.
Verdict: REFUTED · 0 sources for, 3 against · Last checked
Evidence against · 3
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JS-ISH-ESH-1: DRUGS AND SUBSTANCES THAT INCREASE BLOOD PRESSURE. (2023). doi.org. https://doi.org/10.1097/01.hjh.0000914180.78237.39
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More against · 2
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A meta-analysis of effects of selective serotonin reuptake inhibitors on blood pressure in depression treatment: outcomes from placebo and serotonin and noradrenaline reuptake inhibitor controlled trials - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.2147/NDT.S141832
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Depression‐like Symptoms are Associated with Dysbalance in Vascular Norepinephrine Uptake. This is Worsening by Antidepressants and Increases the Risk for Hypertension.. (2015). doi.org. https://doi.org/10.1096/fasebj.29.1_supplement.984.6
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