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the claim

Increased intestinal permeability, or leaky gut, is linked to vitamin D deficiency.

the verdict
INSUFFICIENT LEANING
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that increased intestinal permeability, or leaky gut, is linked to vitamin D deficiency?

Unclear. One review reports that vitamin D/VDR signaling strengthens the intestinal epithelial barrier and reduces paracellular permeability, and another notes vitamin D receptor pathways among factors associated with increased intestinal permeability in IBD. Both are partial, mechanistic or pathway-level indications rather than direct evidence that vitamin D deficiency is linked to leaky gut.

Verdict: PARTIAL LEAN · 2 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 2
Frontiers | Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity
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Frontiers | Relationships Between Vitamin D, Gut Microbiome, and Systemic Autoimmunity. (n.d.). frontiersin.org. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2019.03141/full

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More for · 1
Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation
2025
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Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. (2025). hal.inrae.fr. https://doi.org/10.1007/s00535-025-02289-x

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