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COVID-19 vaccination during pregnancy does not increase the risk of preeclampsia.
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CONTESTED PARTIAL
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5 sources for · 1 against
Is it true that COVID-19 vaccination during pregnancy does not increase the risk of preeclampsia?
Partly. Several cohort and meta-analytic sources report that COVID-19 vaccination in pregnancy was not associated with increased preeclampsia or related hypertensive outcomes, though most address broader perinatal outcome sets rather than preeclampsia specifically. One study of women undergoing assisted reproduction found inactivated vaccination before embryo transfer was associated with increased pregnancy-induced hypertension risk, so the evidence is mixed and only partial.
Verdict: CONTESTED PARTIAL · 5 sources for, 1 against · Last checked
Evidence for · 5
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Maternal and perinatal outcomes of COVID-19 vaccination during pregnancy. (2023). doi.org. https://doi.org/10.4274/jtgga.galenos.2023.2022-9-10
Evidence against · 1
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COVID-19 vaccination and pregnancy-induced hypertension risk in women undergoing assisted reproduction: reproductive epidemiology. (2025). doi.org. https://doi.org/10.1093/humrep/deaf055
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More for · 4
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COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1016/j.eclinm.2026.103785
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Jastrzębski, M., Piątek, M., Hejnosz, A., Szczerba, M., Knysak, K., Maj, A., Wilkowska, K., Kaczorowski, W., Michałowski, M., & Sudomir, M. (2025). COVID-19 and COVID-19 Vaccination in Pregnancy: Epidemiology, Pathophysiology, and Clinical Management. doi.org. https://doi.org/10.12775/qs.2025.46.66635
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COVID-19 vaccination during pregnancy and adverse perinatal outcomes: a systematic review and meta-analysis. (2024). doi.org. https://doi.org/10.1093/trstmh/trad093
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M, R., DK, Y., SW, L., L, B., A, K., L, J., JI, S., & L, S. (2023). Effects of COVID-19 vaccination during pregnancy on SARS-CoV-2 infection and maternal and neonatal outcomes: A systematic review and meta-analysis.. doi.org. https://doi.org/10.1002/rmv.2434
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