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the claim
Prolactin promotes the mRNA synthesis of milk proteins such as beta-casein and alpha-lactalbumin.
the verdict
SUPPORTED
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Recorded sources
2 sources for · 0 against
Is it true that Prolactin promotes the mRNA synthesis of milk proteins such as beta-casein and alpha-lactalbumin?
Yes. Multiple studies demonstrate that prolactin plays a crucial role in promoting the transcription and expression of milk protein genes, including beta-casein and alpha-lactalbumin, during lactogenesis.
Verdict: SUPPORTED · 2 sources for, 0 against · Last checked
Evidence for · 2
Demonstrates that prolactin, alongside other hormones, stimulates beta-casein mRNA expression in mouse mammary epithelium.
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Nishikawa, S., Moore, R. C., Nonomura, N., & Oka, T. (1994). Progesterone and EGF inhibit mouse mammary gland prolactin receptor and beta-casein gene expression. doi.org. https://doi.org/10.1152/ajpcell.1994.267.5.c1467
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More for · 1
Shows that maximal induction of alpha-lactalbumin mRNA in marsupial mammary explants is dependent on prolactin.
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Collet, C., Joseph, R., & Nicholas, K. (1990). Cloning, cDNA analysis and prolactin-dependent expression of a marsupial alpha-lactalbumin. doi.org. https://doi.org/10.1071/rd9900693
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