trustmebro.to/r/…
✓ checked
trust me, bro:
here is the receipt.
the claim

Friedel-Crafts alkylation reactions fail when used with compounds such as nitrobenzene and other strong deactivating systems.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Friedel-Crafts alkylation reactions fail when used with compounds such as nitrobenzene and other strong deactivating systems?

Yes. Friedel-Crafts alkylation reactions generally fail or perform poorly when attempted on strongly deactivated aromatic systems like nitrobenzene due to severe deactivation toward electrophilic attack.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The claim states that Friedel-Crafts alkylations fail with strongly deactivating systems like nitrobenzene. Standard organic chemistry principles and references such as [2], [6], and [9] confirm that strong deactivating groups prevent classical Friedel-Crafts reactions from proceeding unless special activating solvents or conditions are used.

Evidence for · 3
The Alkylation of Aromatic Compounds by the Friedel‐Crafts Method
2011
Get citation
Price, C. C. (2011). The Alkylation of Aromatic Compounds by the Friedel‐Crafts Method. doi.org. https://doi.org/10.1002/0471264180.or003.01

See more details
More for · 2
Iron-Catalyzed Friedel-Crafts Reactions of Unactivated 3-Aryl-Oxetanols Exploiting HFIP Stabilization of Carbocations.
2026
Get citation
MAJ, D., CS, B., TK, M., JJ, R., AJP, W., C, C., & JA, B. (2026). Iron-Catalyzed Friedel-Crafts Reactions of Unactivated 3-Aryl-Oxetanols Exploiting HFIP Stabilization of Carbocations.. doi.org. https://doi.org/10.1021/acs.joc.6c00762

Hexafluoroisopropanol-assisted Friedel-Crafts alkylation of deactivated alcohols
Get citation
Noël, F. (n.d.). Hexafluoroisopropanol-assisted Friedel-Crafts alkylation of deactivated alcohols. doi.org. https://doi.org/10.70675/03c61dcdza4afz455fz8348za09b594492c5

What does the evidence say?

The claim states that Friedel-Crafts alkylations fail with strongly deactivating systems like nitrobenzene. Standard organic chemistry principles and references such as [2], [6], and [9] confirm that strong deactivating groups prevent classical Friedel-Crafts reactions from proceeding unless special activating solvents or conditions are used.

Receipt History
Anyone with this link can read the claim and its public receipt, including any personal information in that text. Open permanent receipt.
Check your own claim
Challenge the receipt
Requests are recorded for review. This does not start an automatic check or guarantee a response time.

See the evidence timeline

Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.

This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work