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the claim

HPV vaccine effectiveness increases with the age at which it is given.

the verdict
REFUTED
the evidence says no
Recorded sources
0 sources for · 3 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that HPV vaccine effectiveness increases with the age at which it is given?

No. A 2023 systematic review of 21 studies found the highest HPV vaccine effectiveness in the youngest age group, with 74–93% effectiveness at ages 9–14 versus 12–90% at ages 15–18, indicating effectiveness declines rather than increases with age at vaccination.

Verdict: REFUTED · 0 sources for, 3 against · Last checked

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Evidence against · 3
Human papillomavirus vaccine effectiveness by age at vaccination: A systematic review -
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Human papillomavirus vaccine effectiveness by age at vaccination: A systematic review - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1080/21645515.2023.2239085

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More against · 2
Quadrivalent HPV Vaccine Effectiveness Against Cervical Intraepithelial Lesion Grade 2 or Worse in Norway: A Registry-Based Study of 0.9 Million Norwegian Women
2024
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Quadrivalent HPV Vaccine Effectiveness Against Cervical Intraepithelial Lesion Grade 2 or Worse in Norway: A Registry-Based Study of 0.9 Million Norwegian Women. (2024). doi.org. https://doi.org/10.1093/infdis/jiae209

Age-Based Programs for Vaccination against HPV
2009
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Age-Based Programs for Vaccination against HPV. (2009). doi.org. https://doi.org/10.1111/j.1524-4733.2009.00512.x

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