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Drinking more than 200 mg of caffeine daily during pregnancy increases the risk of miscarriage.
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CONTESTED PARTIAL
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5 sources for · 1 against
Is it true that drinking more than 200 mg of caffeine daily during pregnancy increases the risk of miscarriage?
Partly. Evidence is mixed and only partial: a 2022 dose-response meta-analysis and a survey report link caffeine or >200 mg/day intake to pregnancy loss, while a 2011 review found no apparent increase in miscarriage risk. None of the retrieved items isolates the specific 200 mg/day threshold for miscarriage in humans.
Verdict: CONTESTED PARTIAL · 5 sources for, 1 against · Last checked
Evidence for · 5
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Jingjing, Q., Qi, C., & M., W. S. (2020). Impacts of Caffeine during Pregnancy. authors.library.caltech.edu. https://doi.org/10.1016/j.tem.2019.11.004
Evidence against · 1
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Caffeine. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Caffeine
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More for · 4
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Relationship between maternal caffeine and coffee intake and pregnancy loss: A grading of recommendations assessment, development, and evaluation-assessed, dose-response meta-analysis of observational studies - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.3389/fnut.2022.886224
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The modifiable and nonmodifiable risk factors for miscarriage. (2016). doi.org. https://doi.org/10.4103/2090-6021.200178
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Alamneh, A. A., Endris, B. S., & Gebreyesus, S. H. (2020). Caffeine, alcohol, khat, and tobacco use during pregnancy in Butajira, South Central Ethiopia. doi.org. https://doi.org/10.1371/journal.pone.0232712
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Joshua, O. O., Joshua, A., & Samson, O. O. (2017). Mother's Caffeine Ingestion Affects Fecundity and Offspring Birth Weight in Murine Models. zenodo.org. https://doi.org/10.9734/AJOB/2017/34230
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