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the claim

Only the coding regions of genes are used to synthesize RNA.

the verdict
REFUTED
the evidence says no
Recorded sources
0 sources for · 4 against

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Is it true that only the coding regions of genes are used to synthesize RNA?

No. The claim that only coding regions of genes are used to synthesize RNA is refuted by established biological knowledge and multiple studies showing that non-coding genes and regions (such as lncRNAs) are extensively transcribed.

Verdict: REFUTED · 0 sources for, 4 against · Last checked

Evidence against · 4
Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis
2021
This paper discusses long non-coding RNAs (lncRNAs), which are transcribed RNAs that do not encode proteins, demonstrating that non-coding regions and genes are also transcribed into RNA.
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Saha, C., Laha, S., Chatterjee, R., & Bhattacharyya, N. P. (2021). Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis. doi.org. https://doi.org/10.3390/ncrna7040074

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More against · 3
Genesis of Non-Coding RNA Genes in Human Chromosome 22—A Sequence Connection with Protein Genes Separated by Evolutionary Time
2020
This study examines long non-coding RNA genes, showing that non-coding genes are transcribed and active alongside protein-coding genes.
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Delihas, N. (2020). Genesis of Non-Coding RNA Genes in Human Chromosome 22—A Sequence Connection with Protein Genes Separated by Evolutionary Time. doi.org. https://doi.org/10.3390/ncrna6030036

Regulation of endometriosis by long non-coding RNA SRA through estrogen receptor: research progress.
2026
This review highlights lncRNA SRA, a non-coding RNA that functions as an RNA transcript and scaffold, proving that RNA synthesis is not restricted to protein-coding regions.
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J, L. (2026). Regulation of endometriosis by long non-coding RNA SRA through estrogen receptor: research progress.. doi.org. https://doi.org/10.62347/rjts1592

Genesis of Non-coding RNA Genes- A Sequence Connection with Protein Genes Separated by Evolutionary Time
2020
This paper discusses the evolutionary genesis of non-coding RNA genes, confirming that the genome transcribes regions outside of protein-coding genes.
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Delihas, N. (2020). Genesis of Non-coding RNA Genes- A Sequence Connection with Protein Genes Separated by Evolutionary Time. doi.org. https://doi.org/10.20944/preprints202007.0454.v1

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