✓ checked
trust me, bro:
here is the receipt.
the claim
Coenzyme A is synthesized from vitamin B5, also known as pantothenic acid.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against
Is it true that Coenzyme A is synthesized from vitamin B5, also known as pantothenic acid?
Yes. Coenzyme A is biochemically synthesized from pantothenic acid (vitamin B5) through a multi-step enzymatic pathway initiated by pantothenate kinase.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
The analysis
Multiple biochemical and metabolic studies explicitly confirm that pantothenic acid (vitamin B5) is the primary precursor required for the biosynthesis of coenzyme A.
Evidence for · 3
States that pantothenate is vitamin B5 and serves as the key precursor for the biosynthesis of coenzyme A.
Get citation
Leonardi, R. & Jackowski, S. (2007). Biosynthesis of Pantothenic Acid and Coenzyme A. doi.org. https://doi.org/10.1128/ecosalplus.3.6.3.4
See more details
More for · 2
Shows that microbial pantothenic acid (vitamin B5) is utilized by host pantothenate kinase to synthesize coenzyme A.
Get citation
Z, L., Z, X., T, Y., X, W., C, S., W, X., Y, C., X, H., P, W., M, L., X, H., Y, Z., T, Z., X, J., K, S., T, C., X, W., T, X., L, D., H, L., B, X., H, C., & J, S. (2026). Gut commensal Bacteroides-derived pantothenic acid alleviates metabolic syndrome.. doi.org. https://doi.org/10.1016/j.chom.2026.06.005
Demonstrates that precursors like panthenol and pantethine modulate and increase coenzyme A biosynthesis in the liver.
Get citation
DS, S., PA, A., LD, Z., AV, E., OV, M., NV, A., VA, B., NP, K., AG, M., IB, P., MI, B., EY, P., & DB, Z. (2026). Panthenol Protects Against Oxidative Stress and Liver Fibrosis in Cholestasis in Association with Increased Coenzyme A Biosynthesis.. doi.org. https://doi.org/10.3390/ijms27114913
What does the evidence say?
Multiple biochemical and metabolic studies explicitly confirm that pantothenic acid (vitamin B5) is the primary precursor required for the biosynthesis of coenzyme A.
Receipt History
Anyone with this link can read the claim and its public receipt, including any
personal information in that text. Open permanent receipt.
Check your own claim
Challenge the receipt
Requests are recorded for review. This does not start an automatic check
or guarantee a response time.
Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.
This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work
Terms · Privacy · How verdicts work