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the claim

Gout is associated with a higher risk of cardiovascular disease and chronic kidney disease.

the verdict
CONTESTED PARTIAL
Recorded sources
3 sources for · 1 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that gout is associated with a higher risk of cardiovascular disease and chronic kidney disease?

Partly. Two cohort studies report that patients with gout have a higher risk of cardiovascular outcomes, and one clinical review notes substantial rates of renal disease and CVD among gout patients. However, no retrieved item directly measures gout as a risk factor for chronic kidney disease, and one genetic study found uric acid variants contributing to gout but not to coronary artery disease.

Verdict: CONTESTED PARTIAL · 3 sources for, 1 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 3
Gout is associated with increased cardiovascular risk: results from analysis of the CPRD dataset
2023
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Gout is associated with increased cardiovascular risk: results from analysis of the CPRD dataset. (2023). doi.org. https://doi.org/10.1093/eurheartj/ehad655.2771

Evidence against · 1
Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease
2009
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Stark, K., Reinhard, W., Grassl, M., Erdmann, J., Schunkert, H., & Illig, T. (2009). Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease. doi.org. https://doi.org/10.1371/journal.pone.0007729

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More for · 2
Major Cardiovascular Events in Patients with Gout and Associated Cardiovascular Disease or Heart Failure and Chronic Kidney Disease Initiating a Xanthine Oxidase Inhibitor -
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Major Cardiovascular Events in Patients with Gout and Associated Cardiovascular Disease or Heart Failure and Chronic Kidney Disease Initiating a Xanthine Oxidase Inhibitor - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://pmc.ncbi.nlm.nih.gov/articles/PMC5726059/

Cardiovascular Disease Prevalence in Patients with Osteoarthritis, Gout, or Both.
2017
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Cardiovascular Disease Prevalence in Patients with Osteoarthritis, Gout, or Both.. (2017). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/27281314

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