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the claim

Melatonin use increases the risk of falls in older adults.

the verdict
CONTESTED PARTIAL
Recorded sources
1 source for · 2 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that melatonin use increases the risk of falls in older adults?

Partly. Evidence is mixed and only partial: one 12-month RCT in postmenopausal women found melatonin did not affect postural balance or falls risk, and a hospital study found only benzodiazepines, not melatonin receptor agonists, associated with falls; however, a claims study in older Parkinson's patients found melatonin receptor agonists significantly increased femoral fracture risk.

Verdict: CONTESTED PARTIAL · 1 source for, 2 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 1
Hypnotics and injuries among older adults with Parkinson’s disease: a nested case–control design
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Hypnotics and injuries among older adults with Parkinson’s disease: a nested case–control design. (n.d.). cir.nii.ac.jp. https://doi.org/10.1186/s12877-023-03944-9

Evidence against · 2
Safety of higher doses of melatonin in adults: A systematic review and meta-analysis.
2022
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Schrire, Z. M., Phillips, C. L., Chapman, J. L., Duffy, S. L., Wong, G., D'Rozario, A. L., Comas, M., Raisin, I., Saini, B., Gordon, C. J., McKinnon, A. C., Naismith, S. L., Marshall, N. S., Grunstein, R. R., & Hoyos, C. M. (2022). Safety of higher doses of melatonin in adults: A systematic review and meta-analysis.. doi.org. https://doi.org/10.1111/jpi.12782

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More against · 1
Association between nocturnal falls and hypnotic drug use in older patients at acute care hospitals
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Association between nocturnal falls and hypnotic drug use in older patients at acute care hospitals. (n.d.). cir.nii.ac.jp. https://doi.org/10.1007/s00228-023-03485-5

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