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the claim
Chronic loneliness increases the risk of premature death and cardiovascular disease.
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INSUFFICIENT LEANING
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6 sources for · 0 against
Is it true that chronic loneliness increases the risk of premature death and cardiovascular disease?
Unclear. Multiple meta-analyses and reviews associate loneliness with increased all-cause mortality, and some reviews also describe loneliness as a cardiovascular risk factor, but the strongest quantitative CVD-mortality finding is for social isolation rather than loneliness, and one study uses a proxy marker in women only. The evidence supports the claim in part, not in full.
Verdict: PARTIAL LEAN · 6 sources for, 0 against · Last checked
Evidence for · 6
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Nakou, A., Dragioti, E., Bastas, N., Zagorianakou, N., Kakaidi, V., Tsartsalis, D., Mantzoukas, S., Tatsis, F., Veronese, N., Solmi, M., & Gouva, M. (2025). Loneliness, social isolation, and living alone: a comprehensive systematic review, meta-analysis, and meta-regression of mortality risks in older adults.. doi.org. https://doi.org/10.1007/s40520-024-02925-1
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More for · 5
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Wang, F., Gao, Y., Han, Z., Yu, Y., Long, Z., Jiang, X., Wu, Y., Pei, B., Cao, Y., Ye, J., Wang, M., & Zhao, Y. (2023). A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality.. doi.org. https://doi.org/10.1038/s41562-023-01617-6
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Loneliness, Social Isolation, and Cardiovascular Health - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1089/ars.2017.7312
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Alun, J. & Murphy, B. (2019). Loneliness, social isolation and cardiovascular risk. doi.org. https://doi.org/10.12968/bjca.2019.0093
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Effects of Chronic and State Loneliness on Heart Rate Variability in Women. (n.d.). cir.nii.ac.jp. https://doi.org/10.1093/abm/kaaa065
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Design of intelligent monitoring of loneliness in the elderly using a serverless architecture with real-time communication API. (2023). doi.org. https://doi.org/10.3233/thc-235006
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Ibon, O., Begonya, G., & Amaia, M. (2023). Design of intelligent monitoring of loneliness in the elderly using a serverless architecture with real-time communication API. zenodo.org. https://doi.org/10.3233/THC-235006
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