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the claim
Amlodipine besylate is a long-acting calcium channel blocker.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
2 sources for · 0 against
Is it true that Amlodipine besylate is a long-acting calcium channel blocker?
Yes. Amlodipine besylate is widely documented in clinical literature as a long-acting calcium channel blocker used in the management of hypertension.
Verdict: SUPPORTED · 2 sources for, 0 against · Last checked
The analysis
The retrieved papers consistently confirm that amlodipine (and amlodipine besylate) is a long-acting calcium channel blocker characterized by an extended plasma half-life and once-daily dosing requirements.
Evidence for · 2
This study explicitly characterizes amlodipine as a long-acting calcium channel blocker with a plasma half-life of 36 hours.
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Ishimitsu, T., Minami, J., Kawano, Y., Numabe, A., & Takishita, S. (1999). AMLODIPINE, A LONG‐ACTING CALCIUM CHANNEL BLOCKER, ATTENUATES MORNING BLOOD PRESSURE RISE IN HYPERTENSIVE PATIENTS. doi.org. https://doi.org/10.1046/j.1440-1681.1999.03072.x
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More for · 1
This paper discusses amlodipine besylate as a calcium channel blocker used for hypertension treatment in long-acting drug delivery systems.
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N, D. T., HC, L., R, Q., DI, V., X, L., CYX, C., & A, G. (2021). Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension.. doi.org. https://doi.org/10.1016/j.nano.2021.102417
What does the evidence say?
The retrieved papers consistently confirm that amlodipine (and amlodipine besylate) is a long-acting calcium channel blocker characterized by an extended plasma half-life and once-daily dosing requirements.
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