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the claim

Cannabidiol reduces seizure frequency in patients with Dravet syndrome and Lennox-Gastaut syndrome.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
9 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Cannabidiol reduces seizure frequency in patients with Dravet syndrome and Lennox-Gastaut syndrome?

Yes. Multiple systematic reviews and meta-analyses of randomized placebo-controlled trials report that adjunctive cannabidiol significantly reduces seizure frequency in patients with Dravet syndrome and Lennox-Gastaut syndrome, with additional cohort and chart-review studies supporting the effect.

Verdict: SUPPORTED · 9 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 9
Dravet syndrome
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Dravet syndrome. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Dravet_syndrome

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More for · 8
cannabidiol
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cannabidiol. (n.d.). cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cannabidiol

Cannabidiol: A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes
2019
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Cannabidiol: A New Hope for Patients With Dravet or Lennox-Gastaut Syndromes. (2019). doi.org. https://doi.org/10.1177/1060028018822124

Cannabidiol for Treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea
2020
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Koo, C., Kim, S. H., Lee, J., Park, B., Lee, H., Kim, H., & Kang, H. (2020). Cannabidiol for Treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea. doi.org. https://doi.org/10.3346/jkms.2020.35.e427

Use of cannabidiol in the treatment of epilepsy: Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex
2022
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Silvinato, A., Floriano, I., & Bernardo, W. (2022). Use of cannabidiol in the treatment of epilepsy: Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex. doi.org. https://doi.org/10.1590/1806-9282.2022D689

2 recorded entries grouped as this source

Additional records of the same source are shown below. They are not counted as additional sources.

Use of cannabidiol in the treatment of epilepsy: Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex -
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Use of cannabidiol in the treatment of epilepsy: Lennox-Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1590/1806-9282.2022D689

Retrospective Chart Review Study of Use of Cannabidiol (CBD) Independent of Concomitant Clobazam Use in Patients with Lennox-Gastaut Syndrome or Dravet Syndrome
2023
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Retrospective Chart Review Study of Use of Cannabidiol (CBD) Independent of Concomitant Clobazam Use in Patients with Lennox-Gastaut Syndrome or Dravet Syndrome. (2023). u-picardie.hal.science. https://doi.org/10.1016/j.seizure.2023.05.003

Adjunctive Cannabidiol for Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis of Randomized Trials Across Syndromes, Formulations, and Dose Ranges.
2026
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R, P., M, M., MA, K., & AY, C. (2026). Adjunctive Cannabidiol for Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis of Randomized Trials Across Syndromes, Formulations, and Dose Ranges.. doi.org. https://doi.org/10.2147/tcrm.s601774

Epilepsy, neuroinflammation and cannabidiol What do we know thus far?
2026
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Ríos, G. P., Perucca, E., Striano, P., Caraballo, R., Ríos, X. P., Pascual-Pascual, S., & Cuesta, G. P. (2026). Epilepsy, neuroinflammation and cannabidiol What do we know thus far?. doi.org. https://doi.org/10.3389/fphar.2025.1749260

Refractory epilepsy in children: current evidence for the use of cannabidiol in Brazil
2025
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Refractory epilepsy in children: current evidence for the use of cannabidiol in Brazil. (2025). doi.org. https://doi.org/10.5327/1516-3180.cpn.1489

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