Immunohistochemistry is a commonly used technique in pathological diagnosis that provides high accuracy, sensitivity, and specificity for tumor diagnosis, classification, and prognosis.
Is it true that Immunohistochemistry is a commonly used technique in pathological diagnosis that provides high accuracy, sensitivity, and specificity for tumor diagnosis, classification, and prognosis?
Yes. Multiple studies consistently demonstrate that immunohistochemistry provides high accuracy, sensitivity, and specificity for tumor diagnosis, classification, and prognostic evaluation across a wide range of malignancies.
Verdict: SUPPORTED · 7 sources for, 0 against · Last checked
The retrieved literature consistently supports the claim by providing multiple recent clinical studies and meta-analyses demonstrating that immunohistochemistry (both individually and in panels) achieves high sensitivity, specificity, and diagnostic accuracy for various tumor types, classifications, and prognostic biomarkers. There are no refuting papers.
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X, H., X, W., & C, L. (2026). Adjunctive diagnostic utility of POU2F3 in predominantly pulmonary high-grade neuroendocrine carcinomas with limited or discordant conventional marker expression: a case-control study.. doi.org. https://doi.org/10.3389/fmed.2026.1886172
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V, T. & G, S. (2026). Diagnostic accuracy of nuclear STAT6 immunohistochemistry for solitary fibrous tumour: a systematic review and meta-analysis.. doi.org. https://doi.org/10.1016/j.anndiagpath.2026.152703
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GH, T., DH, T., LN, N., TA, T., & KA, L. (2026). PRAME immunohistochemistry demonstrates high diagnostic accuracy for distinguishing melanoma from nevi but no observed association with pT stage in cutaneous melanoma: a Vietnamese clinicopathological study.. doi.org. https://doi.org/10.1186/s13000-026-01806-7
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FS, M. A. (2026). Diagnostic utility and tissue localization of HPV16 and HPV18 E7 immunohistochemistry in cervical lesion progression: a comparative study with PCR.. doi.org. https://doi.org/10.3389/fonc.2026.1942646
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Y, Y., J, W., Y, C., H, J., Y, C., S, Y., & Y, Z. (2026). Primary renal synovial sarcoma: a clinicopathological study of 23 cases highlighting the diagnostic value of SS18-SSX, TLE1, and INI1 immunohistochemistry panel.. doi.org. https://doi.org/10.1007/s00428-026-04628-6
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Y, C., R, L., Q, L., & G, H. (2026). Comparison of PCR-based high-resolution melting curve analysis and immunohistochemistry in detecting microsatellite instability in colorectal cancer: a retrospective consistency study.. doi.org. https://doi.org/10.7717/peerj.21607
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M, W., B, P., W, Y., W, X., & J, D. (2026). An immunohistochemical diagnostic panel for Xp11.2 translocation renal cell carcinoma: A diagnostic accuracy study.. doi.org. https://doi.org/10.1097/md.0000000000050027
What does the evidence say?
The retrieved literature consistently supports the claim by providing multiple recent clinical studies and meta-analyses demonstrating that immunohistochemistry (both individually and in panels) achieves high sensitivity, specificity, and diagnostic accuracy for various tumor types, classifications, and prognostic biomarkers. There are no refuting papers.
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