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the claim

Epstein-Barr virus infection can be associated with the development of lymphoproliferative disorders.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
8 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Epstein-Barr virus infection can be associated with the development of lymphoproliferative disorders?

Yes. Multiple clinical studies and reviews establish a well-documented link between Epstein-Barr virus infection and the development of various lymphoproliferative disorders.

Verdict: SUPPORTED · 8 sources for, 0 against · Last checked

The analysis

The retrieved literature extensively documents the association between Epstein-Barr virus and various forms of lymphoproliferative disorders, particularly in transplant settings and through viral oncogenesis mechanisms. No papers refute this association.

Evidence for · 8
Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disorders after Hematopoietic Stem Cell Transplantation: Pathogenesis, Risk Factors and Clinical Outcomes
2020
This review highlights that Epstein-Barr virus is a key contributor to post-transplant lymphoproliferative disorders due to immune system dysfunction.
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Fujimoto, A. & Suzuki, R. (2020). Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disorders after Hematopoietic Stem Cell Transplantation: Pathogenesis, Risk Factors and Clinical Outcomes. doi.org. https://doi.org/10.3390/cancers12020328

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More for · 7
Epstein-Barr virus-associated posttransplant lymphoproliferative disorders: new insights in pathogenesis, classification and treatment
2022
The article discusses pathogenesis and classification of Epstein-Barr virus-associated posttransplant lymphoproliferative disorders.
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Dierickx, D., Pociupany, M., & Natkunam, Y. (2022). Epstein-Barr virus-associated posttransplant lymphoproliferative disorders: new insights in pathogenesis, classification and treatment. doi.org. https://doi.org/10.1097/cco.0000000000000885

Epstein–Barr Virus: A Biological Overview and Clinicopathological Changes of Two Epstein–Barr Virus-Related Lymphoproliferative Disorders in a World Health Organization (WHO) 2017 Report
2018
The WHO report details specific lymphoproliferative diseases associated with Epstein-Barr virus.
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Oliveira, C. C. (2018). Epstein–Barr Virus: A Biological Overview and Clinicopathological Changes of Two Epstein–Barr Virus-Related Lymphoproliferative Disorders in a World Health Organization (WHO) 2017 Report. doi.org. https://doi.org/10.33590/emj/10314974

The IPTA Nashville Consensus Conference on Post-Transplant Lymphoproliferative Disorders After Solid Organ Transplantation in Children: Updates on Classification and Prevention-2026.
2026
Consensus guidelines address post-transplant lymphoproliferative disorders and their well-established link to Epstein-Barr virus infection.
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M, G., MG, M., T, G., U, A., CM, B., O, M., M, Y., & SH, S. (2026). The IPTA Nashville Consensus Conference on Post-Transplant Lymphoproliferative Disorders After Solid Organ Transplantation in Children: Updates on Classification and Prevention-2026.. doi.org. https://doi.org/10.1111/petr.70445

Epstein-Barr Virus: More than Just an Infection.
2026
The review notes that Epstein-Barr virus can promote the development of lymphoproliferative disorders in both immunocompetent and immunosuppressed hosts.
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E, V. d. P., B, V. N., & JC, Y. (2026). Epstein-Barr Virus: More than Just an Infection.. doi.org. https://doi.org/10.3390/v18091048

The molecular pathogenesis of Epstein-Barr virus-associated B-cell lymphoproliferative disorders: a scoping review.
2026
This scoping review outlines the molecular pathogenesis and profile of Epstein-Barr virus-associated B-cell lymphoproliferative disorders.
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J, V., X, H., & T, T. (2026). The molecular pathogenesis of Epstein-Barr virus-associated B-cell lymphoproliferative disorders: a scoping review.. doi.org. https://doi.org/10.1080/17474086.2026.2655963

The role of Epstein-Barr virus in NK/T cell lymphoproliferative disorders: molecular mechanisms and potential therapeutic strategies.
2026
The review details how Epstein-Barr virus can lead to lymphoproliferative disorders originating from T and NK cells.
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M, F., H, K., & LV, T. (2026). The role of Epstein-Barr virus in NK/T cell lymphoproliferative disorders: molecular mechanisms and potential therapeutic strategies.. doi.org. https://doi.org/10.3389/fimmu.2026.1826581

Advances and challenges in experimental models for Epstein-Barr virus research.
2026
The paper notes Epstein-Barr virus is etiologically linked to various malignancies and lymphoproliferative disorders.
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G, W., J, T., T, L., S, G., J, Z., & N, X. (2026). Advances and challenges in experimental models for Epstein-Barr virus research.. doi.org. https://doi.org/10.1002/mlf2.70081

What does the evidence say?

The retrieved literature extensively documents the association between Epstein-Barr virus and various forms of lymphoproliferative disorders, particularly in transplant settings and through viral oncogenesis mechanisms. No papers refute this association.

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