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the claim
SDS-PAGE separates proteins based on molecular weight by imparting a uniform negative charge.
the verdict
COMMON KNOWLEDGE
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the weight of evidence
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Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) separates proteins based on molecular weight by binding to proteins and imparting a uniform negative charge-to-mass ratio, making citations unnecessary for this standard biochemical definition.

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The analysis

The claim describes the foundational, textbook definition of how SDS-PAGE functions in biochemistry (using SDS to denature proteins and confer a uniform negative charge so they separate by size). This is a well-established scientific fact and common knowledge, so no literature citation is required.

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first checked04 Aug 2026
judged → COMMON KNOWLEDGE · 9504 Aug 2026
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