trustmebro.to/r/…
✓ checked
trust me, bro:
here is the receipt.
the claim

Grapefruit juice inhibits the CYP3A4 enzyme and raises blood levels of many prescription drugs.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
8 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Grapefruit juice inhibits the CYP3A4 enzyme and raises blood levels of many prescription drugs?

Yes. Multiple independent sources, including a peer-reviewed review and reference works, state that grapefruit juice inhibits the intestinal CYP3A4 enzyme and thereby raises blood levels of many prescription drugs.

Verdict: SUPPORTED · 8 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 8
Grapefruit
Get citation
Grapefruit. (n.d.). en.wikipedia.org. https://en.wikipedia.org/wiki/Grapefruit

See more details
More for · 7
Grapefruits and CYP3A4
2015
Get citation
Grapefruits and CYP3A4. (2015). biology.stackexchange.com. https://biology.stackexchange.com/questions/27757/grapefruits-and-cyp3a4

Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? -
Get citation
Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? - PMC Lock. (n.d.). pmc.ncbi.nlm.nih.gov. https://doi.org/10.1503/cmaj.120951

Grapefruit Juice and Some Oral Drugs: A Bitter Combination
1999
Get citation
Grapefruit Juice and Some Oral Drugs: A Bitter Combination. (1999). escholarship.org. https://escholarship.org/uc/item/7cn8p8k9

[Flavonoids--bioactive compounds in fruits juice].
2011
Get citation
[Flavonoids--bioactive compounds in fruits juice].. (2011). pubmed.ncbi.nlm.nih.gov. https://pubmed.ncbi.nlm.nih.gov/21500482

Potent Inhibition of Human Cytochrome P450 3A4, 2D6, and 2C9 Isoenzymes by Grapefruit Juice and Its Furocoumarins
Get citation
Potent Inhibition of Human Cytochrome P450 3A4, 2D6, and 2C9 Isoenzymes by Grapefruit Juice and Its Furocoumarins. (n.d.). cir.nii.ac.jp. https://doi.org/10.1111/j.1750-3841.2007.00483.x

Variation in Furanocoumarin Content and New Furanocoumarin Dimers in Commercial Grapefruit ( Citrus paradisi Macf.) Juices
Get citation
Variation in Furanocoumarin Content and New Furanocoumarin Dimers in Commercial Grapefruit ( Citrus paradisi Macf.) Juices. (n.d.). cir.nii.ac.jp. https://doi.org/10.1111/j.1365-2621.2005.tb07178.x

Drug-grapefruit juice interactions.
2000
Get citation
Kane, G. C. & Lipsky, J. J. (2000). Drug-grapefruit juice interactions.. doi.org. https://doi.org/10.4065/75.9.933

Receipt History
Anyone with this link can read the claim and its public receipt, including any personal information in that text. Open permanent receipt.
Check your own claim
Challenge the receipt
Requests are recorded for review. This does not start an automatic check or guarantee a response time.

Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.

This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work