More for · 5
Xist RNA in action: Past, present, and future
2019 · cited by 213
Confirms that the X-linked Xist long noncoding RNA is indispensable for XCI and initiates the process early during development.
Progress toward understanding chromosome silencing by Xist RNA
2020 · cited by 151
Identifies the Xist gene as the master regulator of X chromosome inactivation in mammals, producing a lncRNA that silences X-linked genes.
A lifelong duty: how Xist maintains the inactive X chromosome
2022 · cited by 45
Reiterates that X chromosome inactivation is initiated by the lncRNA Xist, which assembles proteins to trigger gene silencing.
Xist in X chromosome inactivation: mechanisms and disease relevance.
2025 · cited by 3
Describes Xist as a main regulator of mammalian X chromosome inactivation that silences most genes on the X chromosome.
From inactivation to intervention: X chromosome silencing in disease pathogenesis and emerging therapeutic strategies
2025 · cited by 3
Confirms that the Xist gene drives XCI initiation through its long non-coding RNA.