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the claim
Vitamin C supplementation increases blood uric acid levels.
the verdict
INSUFFICIENT LEANING
Recorded sources
0 sources for · 2 against
Is it true that vitamin C supplementation increases blood uric acid levels?
Unclear. Two studies bear on the claim, and both point the other way: a small trial in children on hemodialysis found vitamin C supplementation significantly reduced serum uric acid, and a case-control study in coronary artery disease patients associated higher uric acid with lower serum vitamin C. Neither is a general-population randomized trial of supplementation, so the evidence only partially addresses the claim and leans against it.
Verdict: PARTIAL LEAN · 0 sources for, 2 against · Last checked
Evidence against · 2
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Mashad, G. M. E., El-Sayed, H., & Nosair, N. A. (2016). Effect of vitamin C supplementation on lipid profile, serum uric acid, and ascorbic acid in children on hemodialysis.. doi.org. https://doi.org/10.4103/1319-2442.194602
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More against · 1
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Torkzaban, A., Naeini, A., Hassanzadeh, A., & Namdari, M. (2020). The Relationship between Serum Vitamin C and Uric Acid Levels, Antioxidant Status and Coronary Artery Disease: a Case-Control Study. doi.org. https://doi.org/10.7762/cnr.2020.9.4.307
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