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the claim

Variants on the PolyT sequence have specific functional meanings in gene expression

the verdict

SUPPORTED

the evidence backs this

confidence 83/100

Variants within polyT and related homopolymer tract sequences possess clear functional roles in regulating transcription termination, promoter strength, and gene expression.

Evidence for · 3

Adaptive attenuation of virulence in hypervirulent carbapenem-resistant <i>Klebsiella pneumoniae</i>.

2024 · cited by 16

Variations in polyT and related repeat promoter sequences (such as P11T and P12T) directly control promoter activity and virulence gene expression in Klebsiella pneumoniae.

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More for · 2

Transcription termination and readthrough in African swine fever virus.

2024 · cited by 6

PolyT stretches serve as universal transcription termination signals that dictate transcript processing and gene expression regulation in viral systems.

Programmable multistep CRISPR gene activation via control of RNA polymerase III termination.

2025 · cited by 1

The targeted manipulation and removal of RNA polymerase III polyT termination sequences function as a switch to program gene activation cascades.

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first checked01 Aug 2026

judged → SUPPORTED · 8301 Aug 2026

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