Vaping-related lung injuries are primarily linked to vitamin E acetate in THC-containing products
the verdict
SUPPORTED
the evidence backs this
confidence 78/100
Vaping-related lung injuries, specifically the 2019 EVALI outbreak, are strongly linked to vitamin E acetate found predominantly in illicit THC-containing vaping products. Multiple studies and reviews confirm its detection in affected patients and its role in causing acute pulmonary damage.
Evidence for · 4
Does “Dry Hit” Vaping of Vitamin E Acetate Contribute to EVALI? Simulating Toxic Ketene Formation During E-Cigarette Use
2020 · cited by 2
Simulations and kinetic models show that vitamin E acetate decomposes under vaping conditions to produce toxic ketene gas, contributing to EVALI.
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More for · 3
Vaping-related lung disease: a narrative review.
2026 · cited by 0
The acute impacts of vaping during the major outbreak were characterised by the emergence of EVALI linked to vitamin E acetate exposure.
STUDI LITERATUR : HUBUNGAN VITAMIN E ASETAT PADA ROKOK ELEKTRIK DENGAN KEJADIAN EVALI (E-Cigarette, or Vaping, Product Use Associated Lung injury)
2020 · cited by 0
Literature reviews indicate that a vast majority of EVALI patients tested positive for vitamin E acetate in bronchoalveolar lavage fluid.
Vitamin E acetate – a potential factor in e-cigarette or vaping product use-associated lung injury (EVALI)
2025 · cited by 0
Research highlights the role of vitamin E acetate in the pathophysiology of EVALI, where its thermal breakdown and surfactant disruption cause acute respiratory failure.