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the claim

Tumors associated with Von Hippel-Lindau disease can occur in the brain, spinal cord, kidneys, pancreas, adrenal glands, and reproductive tract.

the verdict
SUPPORTED
the evidence backs this
Recorded sources
3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that tumors associated with Von Hippel-Lindau disease can occur in the brain, spinal cord, kidneys, pancreas, adrenal glands, and reproductive tract?

Yes. Von Hippel-Lindau (VHL) disease is a multisystem genetic disorder characterized by the development of tumors across various organs, including the central nervous system, kidneys, and pancreas.

Verdict: SUPPORTED · 3 sources for, 0 against · Last checked

The analysis

The retrieved literature consistently supports the multi-organ tumor phenotype of Von Hippel-Lindau disease, specifically documenting tumors in the central nervous system, kidneys, and pancreas among other sites. There is no evidence refuting the claim.

Evidence for · 3
Monitoring and treatment patterns of von Hippel-Lindau disease-associated central nervous system hemangioblastomas.
2026
The paper notes that patients with VHL experience manifestations across multiple organ systems.
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E, J., Y, S., J, F., M, M., J, S., & M, S. (2026). Monitoring and treatment patterns of von Hippel-Lindau disease-associated central nervous system hemangioblastomas.. doi.org. https://doi.org/10.1186/s13053-026-00337-y

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More for · 2
Diabetic ketoacidosis associated with pancreatic involvement in a patient with von Hippel-Lindau syndrome: a case report.
2026
The paper discusses VHL-related pancreatic disease alongside a history of central nervous system tumors.
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Y, Z., F, L., X, C., D, G., Y, Z., & H, S. (2026). Diabetic ketoacidosis associated with pancreatic involvement in a patient with von Hippel-Lindau syndrome: a case report.. doi.org. https://doi.org/10.3389/fendo.2026.1880422

Pancreatic Hemangioblastoma in a Patient with von Hippel-Lindau Disease: A Case Report.
2025
The paper details central nervous system, renal, and pancreatic involvement in a patient with von Hippel-Lindau disease.
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N, N., Y, K., K, N., A, S., K, K., N, U., T, O., S, K., Y, N., N, S., A, T., S, O., H, I., K, Y., T, A., S, O., Y, U., T, I., T, I., & E, H. (2025). Pancreatic Hemangioblastoma in a Patient with von Hippel-Lindau Disease: A Case Report.. doi.org. https://doi.org/10.70352/scrj.cr.25-0247

What does the evidence say?

The retrieved literature consistently supports the multi-organ tumor phenotype of Von Hippel-Lindau disease, specifically documenting tumors in the central nervous system, kidneys, and pancreas among other sites. There is no evidence refuting the claim.

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