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the claim

The ortho-effect significantly alters the acidity and basicity of substituted aromatic compounds

the verdict

SUPPORTED

the evidence backs this

confidence 78/100

The presence of ortho-substituents on aromatic compounds exerts distinct steric and electronic influences, frequently referred to as the ortho-effect, which substantially alters their acid-base properties.

Evidence for · 2

Acidity Constants of Boronic Acids as Simply as Possible: Experimental, Correlations, and Prediction.

2024 · cited by 2

Paper [4] demonstrates that ortho-substituted compounds deviate from standard linear free energy relationships due to unique steric and electronic effects on acidity.

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More for · 1

Grids II: Aromatic Acidity and Basicity

2021 · cited by 2

Paper [5] organizes the substituent effects on acidity and basicity for aromatic systems such as benzoic acids and anilines, highlighting structural impacts.

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first checked01 Aug 2026

judged → SUPPORTED · 7801 Aug 2026

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